Extreme altitude can induce a range of cellular and systemic responses.Although it is known that hypoxia underlies the major changes and that the physiological responses include hemodynamic changes and erythropoiesis, the molecular mechanisms and signaling pathways mediating such changes are largely unknown.To obtain a more complete picture of the
The introduction of advanced therapy medicinal products (ATMPs) to the global pharma market has been revolutionizing the pharmaceutical industry and has opened new routes for treating various types of cancers and incurable diseases.In the past two decades, a noticeable part of clinical practices has been devoting progressively to these products.The
Zoysia japonica is a warm-season turfgrass that is extensively used in landscaping, sports fields, and golf courses worldwide.Uncovering the low-temperature response mechanism of Z.japonica can help to accelerate the chervo jacke herren development of new cold-tolerant cultivars, which could be used to prolong the ornamental and usage duration of t
The Science Made Sensible (SMS) program began as a partnership between the University of Miami (UM), Florida, USA, and some public schools in Miami.In this program, postgraduate students from UM work with primary school science teachers to engage learners in science through the use of inquiry-based, hands-on activities.Due to the success of the SMS
Interactive evolutionary algorithms (IEAs) coupled with a data-driven user surrogate model (USM) have recently been proposed for enhancing personalized recommendation performance.Since the USM arcade smokey the bear belt relies on only one model to describe the full range of user preferences, existing USM-based IEAs have not investigated how knowle